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Reading centers provide centralized high-quality diagnostics in ophthalmic clinical trials. Since ophthalmic images are captured in electronic format at peripheral clinics, an integrated workflow for image transfer and creation of structured reports is needed, including quality assurance. The image portal and the study database are separate components. We assessed whether this integration is feasible with trial-related IT standards and built a prototype system as a proof-of-concept. CDISC ODM and OAuth authentication were used to integrate the image portal with x4T-EDC, facilitating automatic data transfer and single sign-on.
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